Cleaning / Sterilization in Place: design, construction, automation & validation
Cleaning / Sterilization in Place
In today’s pharmaceutical operations, Cleaning-in-Place (CIP) and Sterilization-in-place (SIP) play a key role in the avoidance of cross-contamination and guaranteeing the sterility of drug processing equipment. These systems can only be designed with great technical skill and knowhow of the process critical parameters.
Agidens CIP and SIP systems are designed to automate critical cleaning and sterilization processes in a controlled and documented way providing the following functionalities:
- Leak testing
- Pre and final rinses
- Chemical washes
- Blow down and air drying
- Vacuum
- Sterilization
- Concentration and temperature/pressure controls
- Sterility monitoring
Agidens Life Sciences for CIP / SIP
As a specialist in cleaning and sterilization of pharmaceutical processes our engineers understand the criticalities in your cleaning and disinfections processes and the strict regulation (GMP guidelines and 21 CFR part 11) which apply. The combination of our process knowhow, our automation skills and cGMP compliance expertise makes us unique as a supplier to the Life Sciences industry.
- Concept study
- BOD (Basis Of Design)
- Detailed engineering
- Risk Analysis
- Mechanical and electrical construction
- Automation (PLC & SCADA/HMI)
- Commissioning & Qualification
- CE Certification
- Cleaning validation & Process validation
Mobile ACIP GMP: mobile CIP for flexible cleaning
In many cases, CIP is integrated in the processing installation, but in some situations, a mobile CIP is more convenient. Agidens applied Mobile ACIP GMP to develop a mobile and compact solution with flexible CIP recipes, which are used to determine the cleaning process based on temperature, time, flow and detergents (Sinner’s Circle).
How can we help?
Is it Agidens Life Sciences you’re looking for? We’re eager to hear your questions or challenges.